Semnan University Press Progress in Physics of Applied Materials 2783-4794 5 1 2024 12 21 Numerical Study of the Role of Nanoparticles in Breast Tumor Treatment in 3D 23 30 9207 10.22075/ppam.2024.34628.1107 EN Abdol Jabbar Shokri Department of Science, Payame Noor University, Sananda, Iran 0000-0002-9701-9220 Hamed Heidari Department of Physics, Varamin Region, Directorate of Education Journal Article 2024 09 07 In this paper, we conducted a numerical study to investigate the role of magnetic nanoparticles (MNPs) in the treatment of cancerous tissues in three dimensional. First, we considered the governing equations associated with this method. Next, we utilized the finite element method (FEM) and Comsol Multiphysics software package to calculate parameters such as temperature distribution, generated heat, and the fraction of damage in tumor and normal tissues over a 40-minute period. The applied frequencies and current in the coil were 150 and 300 kHz and 550 A, respectively. Our calculations revealed that the maximum temperatures of the tumor at frequencies of 150 and 300 kHz were 45.4 and 47 degrees, respectively. These temperatures are sufficient to destroy cancer cells. Furthermore, the comparison of results at 150 and 300 kHz frequencies demonstrated that parameters such as temperature, heat, and degradation rate increase with the increase of frequency. Additionally, we found that the tumor damage at the end of the process for frequencies of 150 and 300 kHz was 100% in the center of the tumor, but reduced to 63% and 75% at the border, respectively. https://ppam.semnan.ac.ir/article_9207_d26b10ca0de48de1619fcefc39d00d64.pdf